The most popular interpretation is the 2022 song “Unholy” by Sam Smith and Kim Petras. It is a sexually charged electropop, dance-pop, and synth-pop song with choral and hyperpop influences, which marked a shift away from ballads for Smith. The lyrics are about a family man who cheats on his wife at a strip club.
In a more general sense, “unholy” refers to something that is considered wicked, evil, or sacrilegious. There are many songs that could be considered unholy based on their themes or content. For example, “Highway to Hell” by AC/DC is a song about a road that leads to hell. ” Sympathy for the Devil” by The Rolling Stones is a song about the devil.